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Coenzyme Q 1O with
Tocotrienols
Background
In 1957, Professor E.L. Crane
discovered Coenzyrne Q10 at the University of Wisconsin. In 1958, its chemical
structure was reported by Dr. D.E. Wolf who worked under Dr. Karl Folkers at
Merck Laboratories. Although Merck could have applied Coenzyme Q10 as a new
drug with the FDA, they decided it was not viable since CoQ10 is a natural
substance that cannot be patented. The nutritional value of Coenzyrne Q10 is
well documented. It is a nutrient that is critical for energy production. CoQ10
is a true coenzyme and an essential component of the mitochondria. New
bioavailability studies have shown that CoQ10 emulsified in rice bran oil
tocotrienols is far superior to CoQ10 powder. These studies were conducted in
response to the clinical trials by Drs. Folkers and Langsioen.
Vitamin E is the term used for two
related homologous groups of naturally occurring essential fat soluble
nutrients that differ only in side chain saturation: the tocopherols, with a
saturated side chain, and the tocotrienols, with an all unsaturated farnesyl
side chain. The free radical quenching activity of Vitamin E in biological
membranes has been well documented, and Vitamin E is believed to be an
important nutrient involved in many biological systems.
The tocotrienols now are known to have
an effect on cholesterol metabolism that appears not to be exhibited by the
tocopherols. Recent research has also provided information on the relative
antioxidant activities of different Vitamin E components. Differences in the
antioxidant activities of tocopherols and tocotrienols are likely to be related
to properties that affect their incorporation in cell membranes. Serbinova and
colleagues attributed that the greater antioxidant capacity of alpha
tocotrienol may, in part, be due to factors that affect accessibility between
lipid radicals and antioxidant. The reactive site of tocopherols, on the other
hand, with a saturated side chain that interacts hydrophobically with acyl side
chains of membrane phospholipids, may be relatively less able to access lipid
radicals due to steric hindrance.
Recommendations for Intake
As a dietary supplement, one (1)
softgel capsule one to three times per Intake day with meals, or as directed by
a physician.
Contents
Each softgel capsule contains 100 mg
Coenzyme Q10, 15 mg Tocotrienols, 397 mg Rice Bran Oil, 2 mg Ascorbyl
Palmitate, and 1 mg of Vitamin E with mixed tocopherols. Available in bottles
of 60 or 200 softgels.
The statements made herein have not
been evaluated by the U.S. Food and Drug Administration. This product is not
intended to diagnose, treat, cure, or prevent any disease.
Certain persons considered to be
experts might disagree with one or more of the foregoing statements concerning
relationships of various nutritional factors to structures and functions of the
body, or various nutritional situations adjunctive to certain bodily
conditions. The same are deemed, nevertheless, to be based on sound and
reliable authorities. No such statement shall be construed as claims or
representations that any Allergy Research Group products, which are foods and
foods for special dietary use, are offered for the diagnosis, cure, mitigation,
treatment, or prevention of any disease.
For Product Availability:
CoQ10 w
Tocotrienols - 200 soft gels
CoQ10 w Tocotrienols
- 60 soft gels |
