Serine is a nonessential amino acid, which means that it
is manufactured from other amino acids in the liver; it does not have to be
obtained directly through the diet.
Serine stimulates the synthesis of glucose (blood sugar)
in the liver. For this reason, eating proteins foods that are rich in serine
will help stabilize the body against oscillations of blood sugar levels after
eating. Serine is known to be the precursor to cysteine, along with methionine.
It is also the precursor to glycine. Serine works in conjunction with alanine
and glycine to help stabilize blood sugar and provide a timed-release source of
glucose after glycogen depletion.
Deficiencies of a nonessential amino acid will not occur
if a well-balanced diet is consumed because the intake of proper foods will
allow the body to produce exactly the amount of amino acid required to function
optimally. Recently serine has been administered along with alanine and glycine
to help management of blood sugar problems associated with reactive
hypoglycemia. Therapeutic doses of serine range between 300 and 1,000 mg per
Serine is readily metabolized and has a wide safety